陈其宾

发布者:李素珍发布时间:2022-10-09浏览次数:427


个人简介:

陈其宾,博士,校聘副教授,硕导,江西省“双千计划”创新领军(青年)人才;先后于四川大学华西药学院取得理学学士学位,中国科学院大学取得理学硕士、博士学位;2017-2019年在中国医学科学院药物研究所从事博士后研究工作;20201月至今受聘于maxbextx官方网站手机登录|首頁|欢迎您生命科学学院。

主要从事抗生素药物的发现及生物合成研究,研究方向包括:1)新型抗生素的挖掘及其生物合成机制的解析;2)特殊催化功能酶的发现及其催化机制的解析;3)特殊功能酶的进化改造及其在药物合成中的应用;至今,已解析三大类潜在抗生素类药物分子的生物合成机制,研究成果先后发表于Journal of the American Chemical SocietyOrganic LettersJournal of Natural Products国际著名期刊上。目前已发表SCI学术论文15余篇,已获授权中国发明专利8项,先后主持国家和省部级项目5项。

真诚欢迎优秀的您加入本课题组共同成长、共创辉煌!有意加入本课题组的准硕士研究生可联系导师:18710068162,邮箱:chenqibin10@mails.ucas.ac.cn

近五年代表作:

  1. Qibin Chen*, Guanyin Yuan, Tao Yuan, Huiting Zeng, Zheng-Rong Zou, Zong-cai Tu, Jie Gao*, and Yi Zou*. Set of cytochrome P450s cooperatively catalyzes the synthesis of a highly oxidized and rearranged diterpene-class sordarinane architecture. Journal of the American Chemical Society2022, 144, 3580−3589.IF=16.383

  2. Qibin Chen#, Jie Gao#, Cooper Jamieson, Jiawang Liu, Masao Ohashi, Jian Bai, Daojiang Yan, Bingyu Liu, Yongsheng Che, Yanan Wang, K. N. Houk*, Youcai Hu*. Enzymatic intermolecular hetero-Diels–Alder reaction in the biosynthesis of tropolonic sesquiterpenes. Journal of the American Chemical Society2019, 141, 14052−14056.IF=16.383

  3. Daojiang Yan#, Qibin Chen#, Jie Gao#, Jian Bai, Bingyu Liu, Yalong Zhang, Le Zhang, Chen Zhang, Yi Zhou, Youcai Hu*. Complexity and diversity generation in the biosynthesis of fumiquinazoline-related peptidyl alkaloids. Organic Letters2019, 21, 1475−1479.Co-first author, IF=6.072

  4. Qi-Bin Chen, Jie Gao, Guo-An Zou, Xue-Lei Xin, Haji Akber Aisa*. Piperidine alkaloids with diverse skeletons from Anacyclus pyrethrum. Journal of Natural Products2018, 81, 1474−1482.IF=4.803

  5. Qi-Bin Chen, Haji Akber Aisa*. Alkaloid constituents from Viola tianschanica. Phytochemistry2017, 144, 233–242.IF=4.004

  6. Dan Tang, Qi-Bin Chen, Xue-Lei Xin*, Haji-Akber Aisa*. Anti-diabetic effect of three new norditerpenoid alkaloids in vitro and potential mechanism via PI3K/Akt signaling pathway. Biomedicine & Pharmacotherapy2017, 87, 145–152. IF=7.419